March 19, 2025 | UR Gate
Maltose: Structure, Properties, Biological Importance, and Metabolism

1. Introduction
Maltose is a disaccharide that belongs to the carbohydrate family. It is commonly known as malt sugar because it is formed from the enzymatic breakdown of starch. Maltose plays an essential role in various biological and industrial processes, including digestion, brewing, and fermentation.
2. Chemical Structure and Physical Properties
Maltose has the molecular formula C12H22O11 and consists of two glucose molecules linked by an α-1,4-glycosidic bond.
Properties:
- Solubility: Highly soluble in water.
- Taste: Moderately sweet.
- Reactivity: Undergoes hydrolysis, fermentation, and Maillard reactions in food chemistry.
3. Maltose Metabolism
Maltose metabolism involves its breakdown into glucose molecules for absorption in the small intestine. This process is catalyzed by the enzyme maltase.
3.1 Hydrolysis of Maltose
- The enzyme maltase, located in the small intestine, hydrolyzes maltose into two glucose molecules.
- These glucose molecules are then absorbed into the bloodstream and utilized for energy production.
3.2 Absorption and Utilization
- Glucose, derived from maltose hydrolysis, follows the glycolysis pathway, where it is converted into pyruvate and generates ATP.
- In the presence of oxygen, pyruvate enters the citric acid cycle (Krebs cycle) and is further metabolized to produce more ATP through oxidative phosphorylation.
3.3 Maltose in Digestion and Fermentation
- Dietary starch is broken down into maltose by the enzyme amylase before further hydrolysis by maltase.
- Maltose is an essential fermentable sugar used in brewing and baking, where yeast ferments it into ethanol and carbon dioxide.

4. Effects of Maltose on Health
4.1 Benefits
- Provides energy for cellular metabolism.
- Aids digestion as an intermediate product of starch breakdown.
- Supports fermentation in food industries, contributing to the production of beer and bread.
4.2 Risks
- Excess maltose intake may contribute to high blood sugar levels and metabolic disorders if not regulated.
- Malabsorption issues may arise in individuals with enzyme deficiencies, leading to gastrointestinal discomfort.
5. Conclusion
Maltose is an essential disaccharide involved in digestion and energy metabolism. It serves as a key intermediate in starch breakdown and plays a vital role in fermentation processes. Understanding its metabolism helps in better dietary management and industrial applications.